TC287

Evaluation of P450 humanized mouse model (8HUM) as a tool to assess the impac

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Principal Investigator (PI)

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Project location

the sponsor

Home Institution

University of Dundee

Go to PI affiliation web
foundation funding

Foundation funding

The Foundation is providing £293,389.000 in support.

Open Labs Fellow/s

Alastair Kenneth - Kevin Sebastian Coquelin

Project Participant/s

Alastair Kenneth - Kevin Sebastian Coquelin

GSK’s contribution

GSK contribution will make a significant impact on the project. Mainly, related to GSK platform access and as well, scientif

Project Description

Publications 1

Proceedings of the National Academy of Sciences of the United States of America, 121(7)

Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism

MacLeod, A. K., Coquelin, K. S., Huertas, L., Simeons, F. R. C., Riley, J., Casado, P., Guijarro, L., Casanueva, R., Frame, L., Pinto, E. G., Ferguson, L., Duncan, C., Mutter, N., Shishikura, Y., Henderson, C. J., Cebrian, D., Wolf, C. R., & Read, K. D.

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